منابع مشابه
The central and peripheral circulation during and after sodium nitroprusside induced hypotension in the rat.
Central haemodynamics and regional blood flow were investigated during and after sodium nitroprusside (SNP) infusion in halothane anaesthetized rats. The administration of SNP 40 micrograms kg-1 min-1, decreased mean arterial pressure (MAP) to 52 (mean) mm Hg. Cardiac output (CO) remained unchanged, while heart rate (HR) and systemic vascular resistance (SVR) decreased. The regional blood flow ...
متن کاملSodium Nitroprusside Injection
Except when used briefly or at low (< 2 mcg/kg/min) infus ion rates , sodium nitropruss ide gives rise to important quantities of cyanide ion, which can reach toxic, potentially lethal levels (see WARNINGS). The usual dose rate is 0.5 to 10 mcg/kg/min, but infus ion at the maximum dose rate should never las t more than 10 minutes . If blood pressure has not been adequately controlled after 10 m...
متن کاملNitroprusside and cyanide.
Sir,—An otherwise excellent and thorough report by Vesey, Cole and Simpson (1976) fails to acknowledge or refute a hypothesis which has already appeared in this Journal (Smith and Kruszyna, 1976a) about the mechanism by which cyanide is released from nitroprusside in vivo, and the significance of that reaction for blood cyanide concentrations. We are delighted with the confirmation that "The re...
متن کاملEffect of Nitroprusside
In order to evaluate the circulatory action of vasodilator therapy in patients with significant mitral regurgitation, sodium nitroprusside was infused intravenously in 14 patients who had mitral regurgitation due to a variety of causes. In 13 of these patients, valvular insufficiency had been present for several years. The mean arterial pressure fall from 88 ± 1.2 to 71 ± 2.1 mm Hg was accompan...
متن کاملComplication of nitroprusside therapy.
Gated cardiac blood pool scans were obtained using a single crystal Anger camera with a general purpose collimator. In vivo labelling of the red blood cells with 20 mCi of technetium activity was done and a best septal view was obtained. The acquired data were processed using an Elscint AQ-75, DPT-3 acquisition unit equipped with the Dycom-80 program. Each cardiac cycle was divided into 24 fram...
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ژورنال
عنوان ژورنال: Circulation
سال: 1978
ISSN: 0009-7322,1524-4539
DOI: 10.1161/01.cir.58.3.574